http://dspace.bsu.edu.ru/handle/123456789/46540| Название: | Anticholinergic activity and pharmacokinetic parameters of agent SS-68 with properties of class III antiarrhythmic drugs |
| Авторы: | Bogus, S. K. Kulikov, A. L. Vinakov, D. V. Suzdalev, K. P. Galenko-Yaroshevskii, P. A. |
| Ключевые слова: | medicine pharmacology vagus nerve neurogenic atrial fibrillation indole derivate SS-68 antiarrhythmic action pharmacokinetics |
| Дата публикации: | 2016 |
| Библиографическое описание: | Anticholinergic activity and pharmacokinetic parameters of agent SS-68 with properties of class III antiarrhythmic drugs / S. K. Bogus [et al.] // Research result: pharmacology and clinical pharmacology. - 2016. - Vol. 2, № 3.- P. 3-10. - Doi: 10.18413/2500-235X-2016-2-3-3-10. - Refer.: p. 9-10. |
| Краткий осмотр (реферат): | It was shown that the indole derivate SS-68 (50 and 250 μg/kg intravenous) in acute experiments on cats with neurogenic atrial fibrillation (AF) has a dose-dependent antiarrhythmic action which is associated with the neurotropic influence of this substance, since the suppression of the AF coincides with its anticholinergic effect observed for more than 2 hours, but cardiotropic action at this time was not observed. High antiarrhythmic activity of SS-68 to neurogenic AF may be due to the IKAch inhibition and blockade of M2-cholinergic receptors |
| URI (Унифицированный идентификатор ресурса): | http://dspace.bsu.edu.ru/handle/123456789/46540 |
| Располагается в коллекциях: | Vol. 2, № 3 |
| Файл | Описание | Размер | Формат | |
|---|---|---|---|---|
| Bogus_Anticholinergic_16.pdf | 1.07 MB | Adobe PDF | Просмотреть/Открыть |
Все ресурсы в архиве электронных ресурсов защищены авторским правом, все права сохранены.