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Please use this identifier to cite or link to this item: http://dspace.bsu.edu.ru/handle/123456789/46540
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dc.contributor.authorBogus, S. K.-
dc.contributor.authorKulikov, A. L.-
dc.contributor.authorVinakov, D. V.-
dc.contributor.authorSuzdalev, K. P.-
dc.contributor.authorGalenko-Yaroshevskii, P. A.-
dc.date.accessioned2022-05-02T07:20:37Z-
dc.date.available2022-05-02T07:20:37Z-
dc.date.issued2016-
dc.identifier.citationAnticholinergic activity and pharmacokinetic parameters of agent SS-68 with properties of class III antiarrhythmic drugs / S. K. Bogus [et al.] // Research result: pharmacology and clinical pharmacology. - 2016. - Vol. 2, № 3.- P. 3-10. - Doi: 10.18413/2500-235X-2016-2-3-3-10. - Refer.: p. 9-10.ru
dc.identifier.urihttp://dspace.bsu.edu.ru/handle/123456789/46540-
dc.description.abstractIt was shown that the indole derivate SS-68 (50 and 250 μg/kg intravenous) in acute experiments on cats with neurogenic atrial fibrillation (AF) has a dose-dependent antiarrhythmic action which is associated with the neurotropic influence of this substance, since the suppression of the AF coincides with its anticholinergic effect observed for more than 2 hours, but cardiotropic action at this time was not observed. High antiarrhythmic activity of SS-68 to neurogenic AF may be due to the IKAch inhibition and blockade of M2-cholinergic receptorsru
dc.language.isoenru
dc.subjectmedicineru
dc.subjectpharmacologyru
dc.subjectvagus nerveru
dc.subjectneurogenic atrial fibrillationru
dc.subjectindole derivate SS-68ru
dc.subjectantiarrhythmic actionru
dc.subjectpharmacokineticsru
dc.titleAnticholinergic activity and pharmacokinetic parameters of agent SS-68 with properties of class III antiarrhythmic drugsru
dc.typeArticleru
Appears in Collections:Vol. 2, № 3

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