| DC Field | Value | Language |
|---|
| dc.contributor.author | Polikarpova, A. V. | - |
| dc.contributor.author | Egorova, T. V. | - |
| dc.contributor.author | Lunev, E. A. | - |
| dc.contributor.author | Tsitrina, A. A. | - |
| dc.contributor.author | Vassilieva, S. G. | - |
| dc.contributor.author | Deykin, A. V. | - |
| dc.date.accessioned | 2024-12-19T08:21:02Z | - |
| dc.date.available | 2024-12-19T08:21:02Z | - |
| dc.date.issued | 2023 | - |
| dc.identifier.citation | CRISPR/Cas9-generated mouse model with humanizing single-base substitution in the Gnao1 for safety studies of RNA therapeutics / A.V. Polikarpova, T.V. Egorova, E.A. Lunev [et al.] // Frontiers in Genome Editing. - 2023. - Vol.5.-Art. 1034720. - Doi: 10.3389/fgeed.2023.1034720. | ru |
| dc.identifier.uri | http://dspace.bsu.edu.ru/handle/123456789/64201 | - |
| dc.description.abstract | In this work, CRISPR/Cas9 technology was used to introduce a monobase substitution in exon 6 of the Gnao1 gene to replace the mouse triplet encoding Gly203 (GGG) with a codon used in the human gene (GGA) | ru |
| dc.language.iso | en | ru |
| dc.subject | medicine | ru |
| dc.subject | medical genetics | ru |
| dc.subject | medical genomics | ru |
| dc.subject | genetically modified mice | ru |
| dc.subject | genome editing | ru |
| dc.subject | CRISPR/Cas9 | ru |
| dc.subject | personalized medicine | ru |
| dc.subject | GNAO1 | ru |
| dc.subject | encephalopathy | ru |
| dc.title | CRISPR/Cas9-generated mouse model with humanizing single-base substitution in the Gnao1 for safety studies of RNA therapeutics | ru |
| dc.type | Article | ru |
| Appears in Collections: | Статьи из периодических изданий и сборников (на иностранных языках) = Articles from periodicals and collections (in foreign languages)
|
