http://dspace.bsu.edu.ru/handle/123456789/64181| Title: | Development of murine stem cells with conditional knockout of humanized Snca gene |
| Authors: | Patrakhanov, E. A. Pokrovsky, V. M. Karagodina, A. Yu. Krayushkina, A. M. Zhunusov, N. S. Deykin, A. V. Korokin, M. V. Pokrovsky, M. V. Altukhova, O. B. |
| Keywords: | biology animal genetics murine stem cells α-synuclein neurodegeneration Parkinson’s disease conditional knockout CRISPR/Cas9 |
| Issue Date: | 2022 |
| Citation: | Development of murine stem cells with conditional knockout of humanized Snca gene / E.A. Patrakhanov, V.M. Pokrovsky, Karagodina A.Yu. [et al.] ; Belgorod State National Research University // Фармация и фармакология. - 2022. - Т.10, №6.-С. 525-535. - Doi: 10.19163/2307-9266-2022-10-6-525-535. - Refer.: p. 533-534. |
| Abstract: | As a result of the study, a CRISPR/Cas9-assisted homologous recombination strategy was developed in the genome of mouse embryonic stem cells to create a fully humanized Snca gene encoding α-synuclei |
| URI: | http://dspace.bsu.edu.ru/handle/123456789/64181 |
| Appears in Collections: | Статьи из периодических изданий и сборников (на иностранных языках) = Articles from periodicals and collections (in foreign languages) |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Patrahanov_Development_22.pdf | 1.3 MB | Adobe PDF | View/Open |
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