http://dspace.bsu.edu.ru/handle/123456789/63913
Title: | Anti-osteoporotic action research of nanoparticulated resveratrol and losartan |
Authors: | Koklina, N. U. Gudyrev, O. S. Faitelson, A. V. Rajkumar, D. S. R. Pokrovskii, M. V. Korokin, M. V. Bystrova, N. A. |
Keywords: | medicine bone disease osteoporosis endothelial dysfunction pharmacology losartan resveratrol |
Issue Date: | 2015 |
Citation: | Anti-osteoporotic action research of nanoparticulated resveratrol and losartan / N.U. Koklina, O.S. Gudyrev, A.V. Faitelson [et al.] // Research Journal of Pharmaceutical, Biological and Chemical Sciences. - 2015. - Vol.6, №5.-P. 1530-1537. - Refer.: p. 1536-1537. |
Abstract: | The study demonstrated eight weeks after ovariectomy in female white Wistar rats endothelial dysfunction of bone microvasculature and deterioration of regional blood flow in bone develops, leading to the emergence of generalized osteoporosis. Nanoparticulated forms of losartan and resveratrol, possessing endothelium protective action, effectively prevents the reduction of regional microcirculation in bone tissue, keeping it at the level of intact rats |
URI: | http://dspace.bsu.edu.ru/handle/123456789/63913 |
Appears in Collections: | Статьи из периодических изданий и сборников (на иностранных языках) = Articles from periodicals and collections (in foreign languages) |
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Koklina_Anti-osteoporotic.pdf | 626.13 kB | Adobe PDF | View/Open |
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