DC Field | Value | Language |
dc.contributor.author | Zhukovskaya, O. N. | - |
dc.contributor.author | Eliseeva, N. V. | - |
dc.contributor.author | Vassiliev, P. M. | - |
dc.contributor.author | Pridvorov, G. V. | - |
dc.contributor.author | Grechko, O. Yu. | - |
dc.date.accessioned | 2024-08-23T09:33:45Z | - |
dc.date.available | 2024-08-23T09:33:45Z | - |
dc.date.issued | 2024 | - |
dc.identifier.citation | Synthesis and pharmacological activity of various organic and inorganic salts of phenyl derivatives of imidazobenzimidazole / O.N. Zhukovskaya, N.V. Eliseeva, P.M. Vassiliev [et al.] // Research Results in Pharmacology. - 2024. - Vol.10, №2.-P. 119-133. - Doi: 10.18413/rrpharmacology.10.465. - Refer.: p. 132. | ru |
dc.identifier.uri | http://dspace.bsu.edu.ru/handle/123456789/63428 | - |
dc.description.abstract | The creation of new opioid analgesics that are devoid of the main undesirable effects - euphoria, respiratory depression, tolerance - is an important task for the treatment of pain syndrome. Eighteen salts of 9-pyrrolidinoethyl-(1a), 9-piperidinoethyl-(1b), and 9-morpholinoethyl-2-(4- fluorophenyl)benzo[d]imidazo[1,2-a]imidazole (1c) were synthesized and tested for kappa agonist and analgesic activity | ru |
dc.language.iso | en | ru |
dc.subject | medicine | ru |
dc.subject | pharmacology | ru |
dc.subject | imidazobenzimidazole derivatives | ru |
dc.subject | kappa-opioid agonists | ru |
dc.subject | nociceptive | ru |
dc.subject | neuropathic pain | ru |
dc.subject | opioid analgesics | ru |
dc.subject | quantum chemical modeling | ru |
dc.title | Synthesis and pharmacological activity of various organic and inorganic salts of phenyl derivatives of imidazobenzimidazole | ru |
dc.type | Article | ru |
Appears in Collections: | Vol. 10, № 2
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