http://dspace.bsu.edu.ru/handle/123456789/61423| Title: | Development of quantification methods of a new selective carbonic anhydrase II inhibitor in plasma and blood and study of the pharmacokinetics of its ophthalmic suspension in rats |
| Authors: | Khokhlov, A. L. Yaichkov, I. I. Korsakov, M. K. Shetnev, A. A. Volkhin, N. N. |
| Keywords: | medicine pharmacology stabilization pharmacokinetics selective carbonic anhydrase II inhibitor ophthalmic suspension rats |
| Issue Date: | 2023 |
| Citation: | Development of quantification methods of a new selective carbonic anhydrase II inhibitor in plasma and blood and study of the pharmacokinetics of its ophthalmic suspension in rats / A.L. Khokhlov, I.I. Yaichkov, M.K. Korsakov [et al.] // Research Results in Pharmacology. - 2023. - Vol.9, №4.-P. 53-64. - Doi: 10.18413/rrpharmacology.9.10056. - Refer.: p. 63. |
| Abstract: | The developed methods have been fully validated according to the requirements of Russian and internatonal guidelines and have been successfully used for pharmacokinetic research. It was found that a content of 4-(2-methyl-1,3-oxazole-5-yl)-benzenesulfonamide and its main metabolite in whole blood is significantly higher than in plasma |
| URI: | http://dspace.bsu.edu.ru/handle/123456789/61423 |
| Appears in Collections: | Vol. 9, № 4 |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Khokhlov_Development_23.pdf | 537.69 kB | Adobe PDF | View/Open |
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