| DC Field | Value | Language |
|---|
| dc.contributor.author | Kravchenko, A. D. | - |
| dc.contributor.author | Pyatigorskaya, N. V. | - |
| dc.contributor.author | Brkich, G. E. | - |
| dc.contributor.author | Yevsieieva, L. V. | - |
| dc.contributor.author | Kyrychenko, A. V. | - |
| dc.date.accessioned | 2022-05-11T14:32:31Z | - |
| dc.date.available | 2022-05-11T14:32:31Z | - |
| dc.date.issued | 2022 | - |
| dc.identifier.citation | Synthesis, molecular docking, ADMET study and in vitro pharmacological research of 7-(2-chlorophenyl)-4-(4-methylthiazol-5-yl)-4,6,7,8-tetrahydroquinoline-2,5(1H,3H)-dione as a promising non-opioid analgesic drug / A.D. Kravchenko [et al.] // Research Results in Pharmacology. - 2022. - Vol.8, №1.-P. 1-11. - Doi: 10.3897/rrpharmacology.8.80504. | ru |
| dc.identifier.uri | http://dspace.bsu.edu.ru/handle/123456789/46672 | - |
| dc.description.abstract | The discovery of novel drugs that can block the transmission of pain signals for treating the pain of various etiologies is an urgent topic in pharmaceutics. The aim of this paper is to synthesize and to investigate in vitro and in silico characteristics of a promising novel compound: 7-(2-chlorophenyl)-4-(4-methylthiazol-5-yl)-4,6,7,8-tetrahydroquinoline-2,5(1H,3H)-dione (HSV-DKH-0450) | ru |
| dc.language.iso | en | ru |
| dc.subject | medicine | ru |
| dc.subject | pharmacology | ru |
| dc.subject | antagonist | ru |
| dc.subject | drug discovery | ru |
| dc.subject | ion channels | ru |
| dc.subject | molecular docking | ru |
| dc.subject | TRPA1 | ru |
| dc.subject | TRPV1 | ru |
| dc.subject | non-opioid analgesic drug | ru |
| dc.title | Synthesis, molecular docking, ADMET study and in vitro pharmacological research of 7-(2-chlorophenyl)-4-(4-methylthiazol-5-yl)-4,6,7,8-tetrahydroquinoline-2,5(1H,3H)-dione as a promising non-opioid analgesic drug | ru |
| dc.type | Article | ru |
| Appears in Collections: | Vol. 8, № 1
|
