The methodology of assessing the effectiveness of the therapy

Abstract

To substantiate the methodology for assessing the effectiveness of drug therapy, based on the effect of therapy not only on the target organ or function, but also on the regulatory and adaptive status (RAS) of the organism. The cardio-respiratory synchronism test (CRS), proposed as one of the rationale for the concept of the hierarchical system of cardiac rhythmogenesis in an integral organism, was used to evaluate the RAS, since it characterizes the complex reaction of the two most important vegetative functions - respiratory and cardiac