New approaches to prevention of NSAID-gastropathy

Abstract

At present, the issue of gastric mucosal damage, induced by the use of nonsteroidal anti-inflammatory drugs, remains unresolved. The development of new methods of prevention of NSAID-gastropathies with oral coursework use of taurine and procaine, as well as the study of cellular mechanisms of the damaging effect of diclofenac sodium and Ketorolac tromethamine. The methodological approach was based on a range of theoretical, pharmacological, histological, statistical, biophysical methods