http://dspace.bsu.edu.ru/handle/123456789/46308| Название: | Efficacy of liposomal dosage forms and hyperosmolar salines in experimental pharmacotherapy of acute lung injury |
| Авторы: | Kulikov, O. A. Ageev, V. P. Marochkina, E. E. Dolgacheva, I. S. Minayeva, O. V. |
| Ключевые слова: | medicine pharmacology N-acetylcysteine acute lung injury aprotinin Cyanine-7 dexamethasone HyperHAES hypertonic saline liposomes |
| Дата публикации: | 2019 |
| Библиографическое описание: | Efficacy of liposomal dosage forms and hyperosmolar salines in experimental pharmacotherapy of acute lung injury / O.A. Kulikov [et al.] // Research Results in Pharmacology. - 2019. - Vol. 5, № 2.- P. 23-41. - Doi: 10.3897/rrpharmacology.5.35529. - Refer.: p. 39-40. |
| Краткий осмотр (реферат): | Hypertonic sodium chloride solutions and liposomal drugs with pulmotropic effect are of great interest for the treatment of acute lung injury (ALI). For the experiment, liposomes with dexamethasone, N-acetylcysteine (NAC), aprotinin and dye Cyanine-7 (Cy-7) were obtained. A liposome analysis was performed by means of spectrophotometry. ALI was modeled in rats by the administration of the damaging agents into the trachea. All the studied therapeutic agents increased the survival rate of the laboratory animals with ALI. The most effective experimental agent was liposomal dexamethasone |
| URI (Унифицированный идентификатор ресурса): | http://dspace.bsu.edu.ru/handle/123456789/46308 |
| Располагается в коллекциях: | Vol. 5, № 2 |
| Файл | Описание | Размер | Формат | |
|---|---|---|---|---|
| Kulikov_Efficacy.pdf | 4.71 MB | Adobe PDF | Просмотреть/Открыть |
Все ресурсы в архиве электронных ресурсов защищены авторским правом, все права сохранены.