Neuroprotective effects of the novel ethylthiadiazole derivatives (LHT 4-15) in male rats

Abstract

The study was performed on male rats of the Wistar line. The animals were simulated with total cerebral ischemia with preliminary administration of LHT 4-15 compounds in doses of 25 and 50 mg/kg for 60 min. The data obtained from the neurological deficit and in the behavioral tests of the experimental groups confirm the theory of the presence of ethylthiadiazole derivatives under the LHT code 4–15 neuroprotective propertie