http://dspace.bsuedu.ru/handle/123456789/66353| Title: | The excretion study of 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide in rats |
| Authors: | Khokhlov, A. L. Yaichkov, I. I. Shetnev, A. A. Korsakov, M. K. Volkhin, N. N. |
| Keywords: | medicine pharmacology urine feces stabilization validation pharmacokinetics excretion rats carbonic anhydrase II inhibitor, N-hydroxysulfonamide |
| Issue Date: | 2025 |
| Citation: | The excretion study of 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide in rats / A.L. Khokhlov, I.I. Yaichkov, A.A. Shetnev [et al.] // Research Results in Pharmacology. - 2025. - Vol.11, №4.-P. 187-198. - Doi: 10.18413/rrpharmacology.11.524. - Refer.: p. 197-198. |
| Abstract: | The 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide (ODASA) is a new carbonic anhydrase II inhibitor for open-angle glaucoma treatment, but the excretion study of this compound has not been performed yet. Aim: Calculation of excretion parameters of ODASA and its metabolites in urine and feces in rats |
| URI: | http://dspace.bsuedu.ru/handle/123456789/66353 |
| Appears in Collections: | Vol. 11, № 4 |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Khokhlov_The excretion_25.pdf | 828.67 kB | Adobe PDF | View/Open |
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