http://dspace.bsuedu.ru/handle/123456789/65887| Title: | The prefrontal cortex as a target for the atypical antipsychotic RU-31 with 5-HT2A antagonistic activity in the treatment of cognitive symptoms |
| Authors: | Kalitin, K. V. Mukha, O. Y. Voynov, V. B. Spasov, A. A. |
| Keywords: | medicine pharmacology atypical antipsychotics benzimidazoles molecular docking prepulse inhibition prefrontal cortex schizophrenia cognitive deficits |
| Issue Date: | 2025 |
| Citation: | The prefrontal cortex as a target for the atypical antipsychotic RU-31 with 5-HT2A antagonistic activity in the treatment of cognitive symptoms / K.V. Kalitin, O.Y. Mukha, V.B. Voynov, A.A. Spasov // Research Results in Pharmacology. - 2025. - Vol.11, №3.-P. 98-108. - Doi: 10.18413/rrpharmacology.11.537. - Refer.: p. 106-108. |
| Abstract: | This study establishes RU-31 as a promising therapeutic agent for the cognitive symptoms of schizophrenia, demonstrating that it reverses deficits in sensorimotor gating and normalizes PFC neuronal activity through selective 5-HT2A antagonism |
| URI: | http://dspace.bsuedu.ru/handle/123456789/65887 |
| Appears in Collections: | Vol. 11, № 3 |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Kalitin_The prefrontal_25.pdf | 725.88 kB | Adobe PDF | View/Open |
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