http://dspace.bsu.edu.ru/handle/123456789/64410| Title: | Identification and synthesis of metabolites of 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide |
| Authors: | Khokhlov, A. L. Yaichkov, I. I. Shetnev, A. A. Panova, V. A. Efimova, Yu. A. |
| Keywords: | medicine pharmacology glaucoma biotransformation selective carbonic anhydrase II inhibitor benzenesulfonamide |
| Issue Date: | 2024 |
| Citation: | Identification and synthesis of metabolites of 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide / A.L. Khokhlov, I.I. Yaichkov, A.A. Shetnev [et al.] // Research Results in Pharmacology. - 2024. - Vol.10, №4.-P. 15-27. - Doi: 10.18413/rrpharmacology.10.498. |
| Abstract: | 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide is a new selective type II carbonic anhydrase inhibitor with local action through instillation into the eyes. For a complete pharmacokinetic study of this drug, it is necessary to detect and synthesize its metabolites for their systemic exposure evaluation |
| URI: | http://dspace.bsu.edu.ru/handle/123456789/64410 |
| Appears in Collections: | Vol. 10, № 4 |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Khokhlov_Synthesis_24.pdf | 542.14 kB | Adobe PDF | View/Open |
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