http://dspace.bsu.edu.ru/handle/123456789/52726| Title: | Study of neuroprotective activity of new acetylcholinesterase inhibitors TVA and TVS in experimental model of Alzheimer’s disease |
| Authors: | Gasparyan, H. V. Buloyan, S. A. Harutyunyan, H. A. Pogosyan, A. E. Arshakyan, L. M. |
| Keywords: | medicine pharmacology acetylcholinesterase inhibitors acute toxicity entorhinal cortex hippocampus histopathological examination neuroprotection Alzheimer’s disease |
| Issue Date: | 2022 |
| Citation: | Study of neuroprotective activity of new acetylcholinesterase inhibitors TVA and TVS in experimental model of Alzheimer’s disease / H.V. Gasparyan [et al.] // Research Results in Pharmacology. - 2022. - Vol.8, №4.-P. 77-88. - Doi: 10.3897/rrpharmacology.8.87431. - Refer.: p. 86-88. |
| Abstract: | Alzheimer’s disease (AD) is a severe neurodegenerative disease characterized by loss of synaptic connection between neurons of the cortex and subcortical regions. Therefore, the study of new AChEIs with less toxic impact and better effectivity is a topical challenge. In view of this, we synthesized novel chemical compounds: TVA and TVS that possess AChEI activity and studied their neuroprotective effect in an experimental AD model |
| URI: | http://dspace.bsu.edu.ru/handle/123456789/52726 |
| Appears in Collections: | Vol. 8, № 4 |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Gasparyan_Study.pdf | 8.74 MB | Adobe PDF | View/Open |
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