http://dspace.bsu.edu.ru/handle/123456789/46652| Title: | Neuroprotective and cerebrovascular effects of endogenous N-Arachidonoyl-GABA and its putative Cox-2 metabolite - GABA conjugate with Prostaglandin E2 |
| Authors: | Mirzoyan, N. R. Khostikyan, N. G. Meliksetyan, V. S. Hakobyan, A. A. Ganshina, T. S. |
| Keywords: | medicine pharmacology PGE2-GABA AA-GABA nimodipine ethylmethylhydroxypyridine succinate (mexidol) focal permanent ischemia global transient ischemia brain tissue lipofuscin cerebral blood flow bicuculline |
| Issue Date: | 2021 |
| Citation: | Neuroprotective and cerebrovascular effects of endogenous N-Arachidonoyl-GABA and its putative Cox-2 metabolite - GABA conjugate with Prostaglandin E2 / N.R. Mirzoyan [et al.] // Research Results in Pharmacology. - 2021. - Vol.7, №3.-P. 49-61. - Doi: 10.3897/rrpharmacology.7.70974. |
| Abstract: | The aim of the study was to compare the neuroprotective and cerebrovascular effects of bioactive, endogenous lipid-N-arachidonoyl-GABA (AA-GABA) and GABA conjugate with prostaglandin E2 (PGE2-GABA) by evaluation of a morphological state of rat brain tissue and lipofuscin levels under the condition of permanent focal brain ischemia, as well as cerebral circulation under the condition of global transient ischemia |
| URI: | http://dspace.bsu.edu.ru/handle/123456789/46652 |
| Appears in Collections: | Vol. 7, № 3 |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Mirzoyan_Neuroprotective.pdf | 2.42 MB | Adobe PDF | View/Open |
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