http://dspace.bsu.edu.ru/handle/123456789/46535| Title: | Experimental investigation of pharmacokinetic properties and the accumulation of zinc when administrated nanoform of zinc hydroxide in a comparative aspect with zinc sulfate |
| Authors: | Larin, S. L. Zvyagintseva, A. R. Habarov, A. A. Budko, E. V. |
| Keywords: | medicine pharmacology pharmacokinetics zoology physiology of animals zinc nanoparticles zinc hydroxide zinc sulfate zinc oxide accumulation |
| Issue Date: | 2016 |
| Citation: | Experimental investigation of pharmacokinetic properties and the accumulation of zinc when administrated nanoform of zinc hydroxide in a comparative aspect with zinc sulfate / S. L. Larin [et al.] // Research result: pharmacology and clinical pharmacology. - 2016. - Vol. 2, № 4.- P. 21-33. - Doi: 10.18413/2500-235X -2016-2-4-21-33. - Refer.: p. 33. |
| Abstract: | The purpose of a preliminary assessment of the biological effect, a comparative study of nanoparticles using test cultures of bakery yeast, the results of which determined the level of inhibition, which was higher than 90%, compared with the figure for the zinc sulfate and the above 145% more compared to the zinc oxide. Investigation was performed on the pharmacokinetic characteristics of the 40 rabbits-males in comparison with that using zinc sulfate, in an enteral or intravenous administration at three dose levels: 10, 50 and 100 mg/kg |
| URI: | http://dspace.bsu.edu.ru/handle/123456789/46535 |
| Appears in Collections: | Vol. 2, № 4 |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Larin_Experimental_16.pdf | 921.52 kB | Adobe PDF | View/Open |
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