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Please use this identifier to cite or link to this item: http://dspace.bsu.edu.ru/handle/123456789/46522
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dc.contributor.authorKravchenko, D. V.-
dc.contributor.authorAvdeeva, N. V.-
dc.contributor.authorKorokin, M. V.-
dc.date.accessioned2022-04-29T09:04:50Z-
dc.date.available2022-04-29T09:04:50Z-
dc.date.issued2016-
dc.identifier.citationKravchenko, D.V. Assessment of the DNA damage level in peripheral blood leukocytes of mice treated orally with Rapitalam in acute and therapeutic doses / D. V. Kravchenko, N. V. Avdeeva, M. V. Korokin // Research result: pharmacology and clinical pharmacology. - 2016. - Vol. 2, № 4.- P. 9-11. - Doi: 10.18413/2500-235 X-2016-2-4-9-11. - Refer.: p. 11.ru
dc.identifier.urihttp://dspace.bsu.edu.ru/handle/123456789/46522-
dc.description.abstractCentre there was performed experimental research, which carried out the identification and quantitative assessment of alkali-labile sites and DNA strand breaks in leukocytes of peripheral blood of male mice treated with Rapitalam. The method is based on the assessment of the integrity of DNA in leukocytes of the whole blood of animals. Rapitalam was administered to animals orally according to 2 schemes: a single acute dose (413 mg/kg, which corresponds to 1/5 LD50 dose) and once daily in a therapeutic dose (3 mg/kg) for 4 daysru
dc.language.isoenru
dc.subjectbiologyru
dc.subjectzoologyru
dc.subjectphysiology of animalsru
dc.subjectdepressionru
dc.subjectratsru
dc.subjectpatientsru
dc.subjectvaldoxanru
dc.subjectfluoxetineru
dc.subjectmelaxenru
dc.subjectpharmaco-EEGru
dc.subjectmedicineru
dc.subjectpharmacologyru
dc.subjectRapitalamru
dc.titleAssessment of the DNA damage level in peripheral blood leukocytes of mice treated orally with Rapitalam in acute and therapeutic dosesru
dc.typeArticleru
Appears in Collections:Vol. 2, № 4

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