DSpace Collection: http://dspace.bsuedu.ru/handle/123456789/46281 2026-04-07T14:06:37Z In vivo study of pharmacokinetic parameters of a new combination drug based on citicoline and memantine http://dspace.bsuedu.ru/handle/123456789/46645 Title: In vivo study of pharmacokinetic parameters of a new combination drug based on citicoline and memantine Authors: Sysuev, B. B.; Salakhetdinov, D. K. Abstract: Based on the obtained results of memantine and citicoline concentrations in bioassays, the main pharmacokinetic parameters of the studied preparations were calculated, the results of which showed the superiority of the developed combination drug over the reference drugs 2021-01-01T00:00:00Z Distribution, excretion and metabolic pathways of a single parenteral administration of kappa-opioid receptor agonist RU-1205 http://dspace.bsuedu.ru/handle/123456789/46644 Title: Distribution, excretion and metabolic pathways of a single parenteral administration of kappa-opioid receptor agonist RU-1205 Authors: Spasov, A. A.; Smirnova, L. A.; Grechko, O. I.; Eliseeva, N. V.; Lifanova, Yu. V. Abstract: The purpose was to study the pharmacokinetic properties of RU-1205 with the previously identified kappa-agonistic and analgesic effects after parenteral administration 2021-01-01T00:00:00Z Screening of anxiolytic properties and analysis of structure-activity relationship of new derivatives of 6-(4-methoxy)-7H-[1,2,4] triazolo [3,4-a] [2,3] benzodiazepine under the code RD http://dspace.bsuedu.ru/handle/123456789/46643 Title: Screening of anxiolytic properties and analysis of structure-activity relationship of new derivatives of 6-(4-methoxy)-7H-[1,2,4] triazolo [3,4-a] [2,3] benzodiazepine under the code RD Authors: Skripka, M. O.; Spasov, A. A.; Maltsev, D. V.; Miroshnikov, M. V.; Yakovlev, D. S. Abstract: Anxiolytic potential and cytotoxic properties of previously synthesized molecules, containing fragments of 2,3-benzodiazepine and 1,2,4-triazole - 6-(4-methoxyphenyl)-7H-[1,2,4] triazolo [3,4-A] [2,3]benzodiazepines under the generic code RD were studied 2021-01-01T00:00:00Z Study to elucidate the pharmacological activity of retinalamin in a rat model of ischemic retinopathy http://dspace.bsuedu.ru/handle/123456789/46642 Title: Study to elucidate the pharmacological activity of retinalamin in a rat model of ischemic retinopathy Authors: Pobeda, A.; Kalatanova, A.; Abasheva, D.; Dolzhikov, A.; Solovev, N. Abstract: Over the past few years, the incidence of retinal ischemic disorders has been increasing, due to a rising prevalence of such socially burdensome diseases as diabetes and hypertension, which ultimately lead to ocular vascular pathology. The identification of new treatment options that would prevent retinal neuron death is a crucial task of modern pharmacology 2021-01-01T00:00:00Z