DSpace Collection: http://dspace.bsuedu.ru/handle/123456789/46271 2026-04-07T13:59:52Z 2026-04-07T13:59:52Z Pharmacological modulation of cell functional activity with valproic acid and erythropoietin Golubinskaya, P. A. Sarycheva, M. V. Burda, S. Y. Puzanov, M. V. Nadezhdina, N. A. http://dspace.bsuedu.ru/handle/123456789/46340 2022-04-27T00:13:55Z 2019-01-01T00:00:00Z Title: Pharmacological modulation of cell functional activity with valproic acid and erythropoietin Authors: Golubinskaya, P. A.; Sarycheva, M. V.; Burda, S. Y.; Puzanov, M. V.; Nadezhdina, N. A. Abstract: Valproic acid (VA) is carboxylic acid with a branched chain, which is used as an antiepileptic drug. VA, which is an antiepileptic drug, is also a teratogen, which causes defects of a neural tube and an axial skeleton, although the mechanisms are not yet fully clear. It is shown that valproic acid reduces the intracellular level of oxygen active forms 2019-01-01T00:00:00Z L-NAME-induced preeclampsia: correction of functional disorders of the hemostasis system with resveratrol and nicorandil Stupakova, E. G. Lazareva, G. A. Gureev, V. V. Dolzhikova, I. N. Zhilinkova, L. A. http://dspace.bsuedu.ru/handle/123456789/46310 2022-04-25T00:04:39Z 2019-01-01T00:00:00Z Title: L-NAME-induced preeclampsia: correction of functional disorders of the hemostasis system with resveratrol and nicorandil Authors: Stupakova, E. G.; Lazareva, G. A.; Gureev, V. V.; Dolzhikova, I. N.; Zhilinkova, L. A. Abstract: Preeclampsia is a formidable disease of the second half of pregnancy, leading to severe complications, including disability and even death. Many authors have recognized the correlation between the severity of preeclampsia and the degree of disturbances in the hemostasis system. In this regard, the objective of this study was to assess inhibition of platelet aggregation and the possibility of its correction with resverŠ°trol and nicorandi 2019-01-01T00:00:00Z Pharmacological correction of endothelial dysfunction using ademethionin and taurine Khadieva, T. A. Pokrovskaya, T. G. Belousova, Y. V. http://dspace.bsuedu.ru/handle/123456789/46309 2022-04-24T00:05:19Z 2019-01-01T00:00:00Z Title: Pharmacological correction of endothelial dysfunction using ademethionin and taurine Authors: Khadieva, T. A.; Pokrovskaya, T. G.; Belousova, Y. V. Abstract: It is noted that ademethionine and taurine have an endothelioprotective effect because of their ability to decrease hyperhomocysteinemia The investigated drugs showed pronounced endothelioprotective activity and can be recommended for further pre-clinical studies 2019-01-01T00:00:00Z Efficacy of liposomal dosage forms and hyperosmolar salines in experimental pharmacotherapy of acute lung injury Kulikov, O. A. Ageev, V. P. Marochkina, E. E. Dolgacheva, I. S. Minayeva, O. V. http://dspace.bsuedu.ru/handle/123456789/46308 2022-04-24T00:04:47Z 2019-01-01T00:00:00Z Title: Efficacy of liposomal dosage forms and hyperosmolar salines in experimental pharmacotherapy of acute lung injury Authors: Kulikov, O. A.; Ageev, V. P.; Marochkina, E. E.; Dolgacheva, I. S.; Minayeva, O. V. Abstract: Hypertonic sodium chloride solutions and liposomal drugs with pulmotropic effect are of great interest for the treatment of acute lung injury (ALI). For the experiment, liposomes with dexamethasone, N-acetylcysteine (NAC), aprotinin and dye Cyanine-7 (Cy-7) were obtained. A liposome analysis was performed by means of spectrophotometry. ALI was modeled in rats by the administration of the damaging agents into the trachea. All the studied therapeutic agents increased the survival rate of the laboratory animals with ALI. The most effective experimental agent was liposomal dexamethasone 2019-01-01T00:00:00Z