DSpace Collection:http://dspace.bsuedu.ru/handle/123456789/462672026-04-07T14:00:57Z2026-04-07T14:00:57Z2-phenyl-1-(3-pyrrolidin-1-il-propyl)-1H-indole hydrochloride (SS-68): antiarrhythmic and cardioprotective activity and Its molecular mechanisms of action (Part II)Bogus, S. K.Galenko-Yaroshevsky, P. A.Suzdalev, K. F.Sukoyan, G. V.Soldatov, V. O.http://dspace.bsuedu.ru/handle/123456789/466282022-05-06T00:16:36Z2018-01-01T00:00:00ZTitle: 2-phenyl-1-(3-pyrrolidin-1-il-propyl)-1H-indole hydrochloride (SS-68): antiarrhythmic and cardioprotective activity and Its molecular mechanisms of action (Part II)
Authors: Bogus, S. K.; Galenko-Yaroshevsky, P. A.; Suzdalev, K. F.; Sukoyan, G. V.; Soldatov, V. O.
Abstract: The molecular mechanisms of the pharmacological action of SS-68 were chosen as the focus for this study. From the point of view of molecular pharmacology, SS-68 can be attributed to an antiarrhythmic drug with a mixed type of action2018-01-01T00:00:00ZA new group of compounds derived from 4-, 5-, 6- and 7-aminoindoles with antimicrobial activityStepanenko, I. S.Yamashkin, S. A.Kostina, Yu. A.Batarsheva, A. A.Mironov, M. A.http://dspace.bsuedu.ru/handle/123456789/466272022-05-06T00:17:44Z2018-01-01T00:00:00ZTitle: A new group of compounds derived from 4-, 5-, 6- and 7-aminoindoles with antimicrobial activity
Authors: Stepanenko, I. S.; Yamashkin, S. A.; Kostina, Yu. A.; Batarsheva, A. A.; Mironov, M. A.
Abstract: Antimicrobial activity of the substituted amides and pyrroloquinolines on the basis of 4-, 5-, 6-, 7-aminoindoles was etermined in our study, as well as the spectra of their action against Gram-positive and Gram-negative microorganisms, which are causative agents of non-specific and certain specific human infectious diseases. Moreover, we evaluated the synthetic potentials of the substituted 4-, 5-, 6-, 7-aminoindoles as the starting compounds for synthesizing a series of indolylamides and pyrroloquinolines. Also, the prospects for targeted synthesis of biologically active compounds based on indole-type aromatic amines were determined2018-01-01T00:00:00ZAssessment of physicians’ and senior medical students’ knowledge in treatment of patients with community-acquired pneumonia: Current results of the KNOCAP projectBontsevich, R. A.Filinichenko, T. S.Gavrilova, A. A.Goncharova, N. Y.Myronenko, O. V.http://dspace.bsuedu.ru/handle/123456789/463732022-04-27T00:16:31Z2018-01-01T00:00:00ZTitle: Assessment of physicians’ and senior medical students’ knowledge in treatment of patients with community-acquired pneumonia: Current results of the KNOCAP project
Authors: Bontsevich, R. A.; Filinichenko, T. S.; Gavrilova, A. A.; Goncharova, N. Y.; Myronenko, O. V.
Abstract: The article represents the results of anonymous prospective surveys within the framework of the KNOCAP multi-centered research project aimed at accessing the knowledge on the fundamental issues in diagnosis and treatment of community-acquired pneumonia. The survey involved 222 students in their fifth- and sixth years in medical institute from Belgorod, Dnepr (Dnipro), Voronezh, Kiev (Kyiv) and Saratov and 110 physicians from Krasnodar, Saratov, Belgorod and Dnepr2018-01-01T00:00:00ZMolecular and cellular mechanisms of acute cytotoxic liver damage as potential biological targets for magnesium-containing cell-protective drugDudina, M. O.Suslova, I. R.Khalzova, M. S.Dergunova, J. V.Kogan, E. A.http://dspace.bsuedu.ru/handle/123456789/463722022-04-27T00:15:46Z2018-01-01T00:00:00ZTitle: Molecular and cellular mechanisms of acute cytotoxic liver damage as potential biological targets for magnesium-containing cell-protective drug
Authors: Dudina, M. O.; Suslova, I. R.; Khalzova, M. S.; Dergunova, J. V.; Kogan, E. A.
Abstract: Many anti-tumor drugs have a high potential for toxic damage to liver cells, which makes it necessary to identify molecular mechanisms of the development of the negative impact of drugs on the liver and to develop effective methods for preventing and correcting this adverse effect2018-01-01T00:00:00Z