DSpace Collection:http://dspace.bsuedu.ru/handle/123456789/462612026-04-07T14:05:16Z2026-04-07T14:05:16ZPhysico-chemical properties of montmorillonite clays and their application in clinical practice (review)Tishin, A. N.Krut, U. A.Tishina, O. M.Beskhmelnitsyna, E. A.Yakushev, V. I.http://dspace.bsuedu.ru/handle/123456789/465722022-05-05T00:20:06Z2017-01-01T00:00:00ZTitle: Physico-chemical properties of montmorillonite clays and their application in clinical practice (review)
Authors: Tishin, A. N.; Krut, U. A.; Tishina, O. M.; Beskhmelnitsyna, E. A.; Yakushev, V. I.
Abstract: The review is devoted to the medical application of montmorillonite clay minerals. Properties and mechanisms of action of enterosorbents. The properties of the enterosorbents include an absorption capacity and active surface. The mechanisms of action include the sorption of toxins in the gastrointestinal tract, the contact effect on the mucosa, enhancing the release of toxins in the gastrointestinal tract, increasing the metabolism and excretion of toxins2017-01-01T00:00:00ZNanoparticles as agents for targeted delivery in the treatment of vascular pathologiesSernov, L. N.Bogachev, I. A.Avtina, T. V.http://dspace.bsuedu.ru/handle/123456789/465712022-05-05T00:11:37Z2017-01-01T00:00:00ZTitle: Nanoparticles as agents for targeted delivery in the treatment of vascular pathologies
Authors: Sernov, L. N.; Bogachev, I. A.; Avtina, T. V.
Abstract: The strategy of treatment of cardiovascular diseases with preparations based on nanoparticles. For the visualization of atherosclerotic plaques, nanoparticles conjugated with indium (111In) based on antibodies bound to LOX-1 receptors of low density were used in mice2017-01-01T00:00:00ZThe main directions for pharmacological correction (combinations of drugs for general anesthesia) of neurological and cognitive disorders in patients with neoplasms of the central nervous systemKolesnikov, A. N.Gorodnik, G. A.Grigorenko, A. P.Mustafin, T. A.Kolesnikov, N. E.http://dspace.bsuedu.ru/handle/123456789/465702022-05-05T00:17:14Z2017-01-01T00:00:00ZTitle: The main directions for pharmacological correction (combinations of drugs for general anesthesia) of neurological and cognitive disorders in patients with neoplasms of the central nervous system
Authors: Kolesnikov, A. N.; Gorodnik, G. A.; Grigorenko, A. P.; Mustafin, T. A.; Kolesnikov, N. E.
Abstract: The aim of the study was to develop a goal-oriented combination of drugs for general anesthesia, based on a retrospective assessment of the baseline level of neurological and cognitive disorders in adults and children at the stage of preparation for surgery for neoplasms of the central nervous system (sub- and supratentorial neoplasms - SubTNN and SupraTNN), and a prospective evaluation of complications in the postoperative period2017-01-01T00:00:00ZTest system for evaluation of the influence of the biological activity of substances on the signal system of NF-κB: focus on the derivatives of 3- hydroxypyridineSkachilova, S. Y.Ragulina, V. A.Kostina, D. A.Burda, Y. E.http://dspace.bsuedu.ru/handle/123456789/465692022-05-05T00:09:31Z2017-01-01T00:00:00ZTitle: Test system for evaluation of the influence of the biological activity of substances on the signal system of NF-κB: focus on the derivatives of 3- hydroxypyridine
Authors: Skachilova, S. Y.; Ragulina, V. A.; Kostina, D. A.; Burda, Y. E.
Abstract: At the first stage of our study, 11 pharmacological agents-inhibitors of NF-κB in vitro were screened with an estimate of the activity of the p65 subunit in mononuclear cells stimulated by bacterial lipopolysaccharide. The most active substances were: mexidol, ethoxidol and the agent under the code XS-9. Further inhibitory activity against NF-κB pharmacological agents was studied on 4 models: L-NAME-induced endothelial dysfunction, staphylococcal sepsis, acute toxic liver damage and acute pancreatitis2017-01-01T00:00:00Z